Teething is a part of the body growth and maturity process and is affected by many factors, both local and systemic. This paper attempts to evaluate possible relationship between teething and concurrent local or systemic symptoms, basing on the data presented by literature. Teething has been the focus of study for paediatricians and paediatric dentists alike for decades now. Nevertheless, the question whether some symptoms concurrent with teething are related to it or just occurring accidentally in time has never been answered. Among main possible concurrent symptoms and signs are: biting, drooling, gum-rubbing, sucking, irritability, wakefulness, ear-rubbing, facial rash, decreased appetite for solid foods, mild temperature, congestion, sleep disturbance, stool looseness, increased stool number, decreased appetite for liquids, cough, rash other than facial rash, fever, vomiting. Teething observations are usually done as a retrospective study, on groups comprising various number of members. The compiled data are noted by parents, rather than qualified medical staff. Available literature does not give a clear answer if teething is preceded by symptoms or signs exclusively specific to it. It is assumed that no symptom can be considered prodromal of teething and in every individual case different potential causative factors should be taken into account, while severe systemic symptoms require medical consultation.