According to the Polish Menopause and Andropause Society, andropause is a period of the male aging process defined by gradually declining production of androgenic hormones (testosterone and dehydroepiandrosterone), growth hormones and melatonin. The drop in hormone production usually occurs in men over 50 years of age. The symptomatology of these disorders includes gradual deterioration in the quality of life, general well-being and professional performance, libido disorders, sexual dysfunction, intellectual impairment and sleep disturbances. The aim of this paper is to present the pathophysiology of andropause, taking into account the clinical and laboratory diagnostic work-up, available treatment modalities as well as myths about the andropausal period. Since the vast majority of men (several million in Poland) experience systemic changes related to andropause, the topic should be approached holistically, with a proper degree of empathy. A variety of therapeutic modalities are available, which should be employed according to defined principles and contraindications. Unfortunately, a large group of men believe that “this is how it is supposed to be at this age and nothing can be done about it – this is just biology.” This belief, however, is a myth and not a reality. It should be fought against, primarily by raising public awareness, applying prophylactic measures and ultimately through medical interventions.